An Overview about the Biology of Skeletal Muscle Satellite Cells
WEBSatellite cells, surrounding myofibers, are considered the primary stem cells in adult skeletal muscle playing a central role in tissue growth and regeneration [5 - 7]. These undifferentiated cells are maintained under quiescent conditions in healthy muscles, being able to repristinate their proliferative activity upon proper stimulation.
The Role of Satellite Cells in Skeletal Muscle Regeneration—The …
WEBSatellite cells are a heterogeneous group of cells that includes stem cells and skeletal muscle progenitor cells. Each skeletal muscle fiber has its own pool of satellite cells that remain inactive until the muscle is damaged.
Satellite cells in human skeletal muscle plasticity - PMC
WEBOct 21, 2015 · In adult skeletal muscle, satellite cells are typically in a quiescent state and reside in a niche between the sarcolemma and basal lamina of their associated muscle fiber. Upon stimulation, i.e., following exercise, satellite cells become activated, and …
Satellite Cells and Skeletal Muscle Regeneration - PubMed
WEBJul 1, 2015 · Muscle satellite cells are a heterogeneous population with a small subset of muscle stem cells, termed satellite stem cells. Under homeostatic conditions all satellite cells are poised for activation by stimuli such as physical trauma or growth signals.
Control of satellite cell function in muscle regeneration and its ...
WEBOct 18, 2021 · Satellite cells are skeletal muscle stem cells that are largely quiescent. They are activated upon muscle damage and differentiate into muscle cells or return to quiescence.
Satellite cells in human skeletal muscle plasticity
WEBOct 21, 2015 · Skeletal muscle satellite cells are considered to play a crucial role in muscle fiber maintenance, repair and remodeling. Our knowledge of the role of satellite cells in muscle fiber adaptation has traditionally relied on in vitro cell and in vivo animal models.
Satellite cells are essential for skeletal muscle regeneration: the ...
WEBHere, we review recent recombination-based studies that have furthered our understanding of satellite cell biology. The clear consensus is that skeletal muscle does not regenerate without satellite cells, confirming their pivotal and non-redundant role.
Satellite cells: the architects of skeletal muscle - PubMed
WEBSatellite cells are essential for skeletal muscle regeneration as they ultimately provide the myogenic precursors that rebuild damaged muscle tissue. Satellite cells characteristically are a heterogeneous population of stem cells and committed progenitor cells.
Differences in muscle satellite cell dynamics during muscle …
WEBJul 6, 2022 · Skeletal muscle is a dynamic tissue that presents excellent regenerative ability and plasticity in response to external and internal changes, and both processes rely on myogenic-committed cells that reside in skeletal muscle, which are known as muscle satellite cells (MuSCs) [1, 2, 3, 4].
Satellite cells, the engines of muscle repair | Nature Reviews ...
WEBDec 21, 2011 · Satellite cells are a heterogeneous population of stem and progenitor cells that are required for the growth, maintenance and regeneration of skeletal muscle. The transcription factors...