Toledo is a city in and the county seat of Lucas County, Ohio, United States. At the 2020 census, it had a population of 270,871, making Toledo the fourth-most populous city in Ohio, after Columbus, Cleveland, and Cincinnati. Toledo is the 85th-most populous city in the United States. It is the principal city of the Toledo metropolitan area, which had 606,240 residents in 2020. Toledo also serves as a major trade center for the Midwest; its port is the fifth-busiest on the Great Lakes.