Ayamonte is a town and municipality of Spain belonging to the province of Huelva, Andalusia. It is located near the border with Portugal on the …Ayamonte is a town and municipality of Spain belonging to the province of Huelva, Andalusia. It is located near the border with Portugal on the mouth of the Guadiana River. According to the 2015 census, the city had a population of 20,357 inhabitants.