Cameron Parish is a parish in the southwest corner of the U.S. state of Louisiana. As of the 2020 census, the population was 5,617. The parish seat is Cameron. Although it is the largest parish by area in Louisiana, it has the second-smallest population in the state, ahead of only Tensas. Cameron Parish is part of the Lake Charles metropolitan statistical ar…Cameron Parish is a parish in the southwest corner of the U.S. state of Louisiana. As of the 2020 census, the population was 5,617. The parish seat is Cameron. Although it is the largest parish by area in Louisiana, it has the second-smallest population in the state, ahead of only Tensas. Cameron Parish is part of the Lake Charles metropolitan statistical area.