Upon binding to the α 2a-adrenergic receptor, these compounds preferentially activated intracellular signaling pathways that were limited to a few subtypes of G proteins.

To test the hypothesis that nonselective blockade of adrenergic receptor (AR) subtypes is superior to selective blockade of AR subtypes in suppressing left ventricular (LV) remodeling induced by ...

This article reviews the current state of knowledge and understanding of the genetic variation present in the three human beta-adrenergic receptor genes.

Vasopressors can act on the alpha-1, beta-1, and beta-2 adrenergic receptors. They also can act on dopamine receptors. These drugs stimulate smooth muscle contraction in the blood vessels.

Using inhibitors of different subtypes of adrenergic receptors—α1-, α2-, and β-ARs—the scientists found that NE shushing synapses required only α1-ARs. This surprised them at first, because engagement ...

β-adrenergic receptor (β-AR) agonists are among the most potent factors regulating cardiac electrophysiological properties. Connexin 43 (Cx43), the predominant gap-junction protein in the heart ...

It bound tightly to 5-HT1, 5-HT-2, and 5-HT-5, but not to the many other serotonin receptor subtypes, histamine, and adrenergic receptors that LSD also binds. JRT quells symptoms of schizophrenia ...

The adrenaline receptor studied is a member of the G protein-coupled receptor (GPCR) family, and this family is the target of one-third of all Food and Drug Administration (FDA)-approved drugs.