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The sugar-phosphate backbone forms the structural framework of nucleic acids, including DNA and RNA. This backbone is composed of alternating sugar and phosphate groups, and defines directionality ...
Sugar: In DNA, the sugar is deoxyribose, while in RNA, it is ribose.The sugar forms the backbone of the nucleic acid strand. Phosphate Group: The phosphate group is attached to the sugar and helps ...
Natural nucleic acids like DNA and RNA have a sugar-phosphate "backbone" and nitrogen-based components; while the nitrogen-based components in SNA and L-aTNA remain the same, they have an amino ...
Peptide nucleic acids (PNAs) are artificial polymers that were originally invented in 1991 to be synthetic mimics of DNA. Instead of having a deoxyribose phosphate backbone like DNA, PNA has a ...
How to cite this article: Amrane, S. et al. Backbone-independent nucleic acid binding by splicing factor SUP-12 reveals key aspects of molecular recognition. Nat.
The market potential of nucleic acid-based therapies have been pushed into the spotlight following the success of the COVID-19 vaccines. With the explosion of RNA-based therapeutics on the scene, ...
Xeno nucleic acids are essential for the development of nucleic acid-based drugs. To be effective, they need to be able to stably bind to natural RNA (a cellular single-stranded version of the DNA ...
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