To understand the structural changes that occur during Bax activation, we determined the crystal structure of a Bax peptide bound to the 6A7 Fab fragment to a resolution of 2.3 Å.

Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis. Cell, 2013; 152 (3): 519 DOI: 10.1016/j.cell.2012.12.031; ...

Bax Structures Shaped like Rings, Arcs and Lines Captured by Super-Resolution Microscopy (IMAGE) Spanish Foundation for Science and Technology ...