Scientists also showed that, for the blood-brain barrier surrounding the mice cerebellum -- a region responsible for muscle coordination -- L6-F4-2 replaced Norrin and activated WNT signaling.

By getting drugs beyond the blood-brain barrier, researchers believe they could better target treatment for Alzheimer’s disease, seizures, and plenty more. So, it’s safe to say it’s been a goal.

T he blood-brain barrier (BBB) regulates the passage of substances between the bloodstream and the brain, permitting essential nutrients and certain drugs to enter, while blocking harmful molecules. 1 ...

Post-Covid "brain fog" could be caused by leaky blood vessels in the brain, a groundbreaking new study out of Ireland has determined. Researchers from Trinity College Dublin recruited 32 patients ...

This is also the first study that shows how quickly the blood-brain barrier closes after being opened by the ultrasound. It closes in the first 30 to 60 minutes after the communication. and this ...

The findings, in mouse models and isolated human brain tissue, were published in Nature Materials in a paper titled ...

The blood-brain barrier (BBB) is a tightly interlaced system of specialized cells that creates a layered semi-permeable membrane that serves a dual purpose: ...

The blood-brain barrier performs a vital function in keeping out toxins and pathogens, but it can become “leaky.” Now Stanford scientists have identified therapeutic molecules that could help ...

The brain is among the most “immune-privileged” of organs primarily through the highly selective permeability of the blood-brain-barrier (BBB), its minimal lymphatic drainage, the presence of ...

The blood-brain barrier effectively acts as a filter between the body’s circulatory system and the brain. However, it also frustrates efforts to deliver drugs directly to the brain for treating ...

While the role of the blood-brain barrier has long been appreciated for its ability to maintain precise control over what molecules can enter the nervous system, very little is known about how the ...