Gene variation in immune system cells lowers heart disease risk ... In this population of more than 1,800 individuals, the researchers showed that a genetic variant of the CX3CR1 receptor, ...

Finally, the investigators evaluated 503 patients with Crohn’s disease, and found that those who carried a homozygous mutation in the CX3CR1 gene showed a reduced immune response to intestinal ...

Rare genetic variants in CX3CR1 and their contribution to the increased risk of schizophrenia and autism spectrum disorders. Translational Psychiatry , 2017; 7 (8): e1184 DOI: 10.1038/tp.2017.173 ...

In the new study, Dr. Iliev and his colleagues largely answered that question by identifying a type of white blood cell, the CX3CR1+ mononuclear phagocyte, as the immune system's major gut fungal ...

The study (“CX3CR1 + Mononuclear Phagocytes Control Immunity to Intestinal Fungi”), published in Science, shows a strong connection between fungi, immunity, and intestinal inflammation and ...

The Weill Cornell researchers studied more than 500 Crohn's disease patients and found that those who carry a homozygous mutation in the CX3CR1 gene have a reduced gut antifungal response much ...

image: This is opportunistic fungus called candida albicans (red) engulfed by CX3CR1+ phagocytes (green) in the gut villi (blue). view more Credit: Dr. Iliyan Iliev and Dr. Irina Leonardi ...

The CX3CR1 blockade also decreased the number of infiltrating F4/80-positive macrophages in damaged kidneys. ... Gene therapy via blockade of monocyte chemoattractant protein-1 for renal fibrosis.

Chiome Bioscience Inc. and Asahi Kasei Pharma Corp. have entered into an exclusive license agreement to develop and commercialize Chiome’s humanized anti-CX3CR1 antibody, PFKR, currently in the ...

Polymorphism in the Microglial Cell-Mobilizing CX3CR1 Gene Is Associated With Survival in Patients With Glioblastoma The clinical records and pathology reports from women who underwent hysterectomy at ...

Polymorphism in the Microglial Cell-Mobilizing CX3CR1 Gene Is Associated With Survival in Patients With Glioblastoma The clinical records and pathology reports from women who underwent hysterectomy at ...