The cannabinoid industry is transitioning from early-stage exploration to scientifically validated, regulatory-backed ...

The cannabinoid cannabidiol, CBD, ... Therefore, the efficacy of CBD in pain relief suggests that its effects may be through a different mechanism of action than THC.

Anandamide behaves as a partial agonist of cannabinoid receptors with slightly greater CB1 than CB2 affinity, but with much lower CB2 than CB1 efficacy.Other endocannabinoids (such as arachidonyl ...

A “Notice of Special Interest” (NOSI) (entitled “Basic Mechanisms of Cannabis and Cannabinoid Action in Cancer”) was posted on May 5 by NIH’s National Cancer Institute, with the intent ...

AEF0117 is the first of a new pharmacologic class, type 1 cannabinoid receptor signaling-specific inhibitors (CB 1-SSi), with a unique mechanism of action and greater safety and efficacy than ...

Researchers from Columbia University Irving Medical Center and the French biopharmaceutical company Aelis Farma conducted clinical trials for a drug intervention designed to treat cannabis use ...

Andrew Huberman, neuroscientist and podcast superstar, shares misinformation about cannabis, but the experts hit back with data and research × Skip to main content ...

THC and CBD in cannabis influence the body in different ways. ... On the flip side, he noted, “CBD does not activate cannabinoid receptors, and its mechanism of action is still debated.” ...

The study shed light on the brain's natural coping mechanisms by uncovering that the amygdala, the emotional center of the brain, can release its own cannabinoids in response to stress. The Brain ...

Counteracts "high" linked to THC. AEF0117 appears to counteract the “high” associated with THC, the primary psychoactive component of cannabis, at the type 1 cannabinoid receptors—the CB1 ...

A University of the Basque Country (UPV/EHU) study proves that the WIN55.212-2 drug protects the brain and reverses the initial cognitive damage caused by dementia, and explains how it works ...