When activated, cannabinoid receptors 1 and 2 tend to reduce pain and inflammation, while a third receptor, TRPV1, promotes the sensation of pain and contributes to inflammation.

A Chinese research team joined forces with Russian and U.S. biologists to obtain the crystal structure of the human type 2 cannabinoid receptor. Their findings will help develop drugs against ...

Testing a cannabinoid drug in disease models. The study explored the impact of WIN55.212-2, a synthetic compound targeting cannabinoid receptors, in rodent models mimicking early stages of ...

New preclinical research shows that cannabinoid cell surface receptor CB1 plays a tumor-suppressing role in human colorectal cancer, scientists report in the Aug. 1 edition of the journal Cancer ...

Now, evidence has emerged that suggests an additional effect results from the cannabinoid pathway, according to a publication in Nature Medicine. Placebo-activated opioid analgesia doesn't work ...

Drugs like marijuana act on naturally occurring receptors in the brain called cannabinoid receptors. However, the mechanisms by which these drugs produce their sensory and mood altering effects ...

Cannabinoids are naturally occurring compounds found in the Cannabis sativa plant. Of over 480 different compounds present in the plant, only around 66 are termed cannabinoids. Skip to content ...

THC’s intoxicating effects boil down to the CB1 cannabinoid receptors. Since the CB1 pathways exist in the central nervous system, anything that binds to those will have psychotropic effects.

While more research is necessary, some sources note that cannabinoid receptors may interfere with molecular pathways in the development of thyroid cancer, and could be potential therapeutic ...

Artelo reports favorable Phase 1 results for its FABP5 inhibitor, showing strong safety data and dose-dependent absorption in ...

Research led by the University of the Basque Country (UPV/EHU) has identified a potential therapeutic pathway involving cannabinoid receptors to counter memory impairment in early stages of ...