Class III, Focal Lupus Nephritis (moderate damage): Some glomeruli are more inflamed with swelling and irritation. Scars may be seen, and the kidneys may not work as well as before. Class IV, Diffuse ...

If you have a patient presenting with severe class 3 or 4 or even class 5 lupus nephritis, how do you pick the right induction agent for that patient? Caster: That's a great question.

Current treatment recommendations for lupus nephritis are largely guided by the 2003 International Society of Nephrology/Renal Pathology Society classification system. Here, the authors discuss ...

Menn-Josephy H, Truman M, Palmen M, Leher H. Efficacy and safety of voclosporin over 3 years in patients with severe lupus nephritis. Presented at: Kidney Week 2022; November 3 to 6, Orlando, Florida.

Lupus Nephritis Pipeline encompasses promising therapies with ... multicenter study to evaluate the efficacy and safety of Obinutuzumab in patients with ISN/RPS 2003 Class III Or IV lupus nephritis.

Association of lupus nephritis histopathologic classification with venous thromboembolism – modification by age at biopsy. Published online February 25, 2021. Kidney Int Rep. doi:10.1016/j.ekir ...

Adding the anti-CD20 monoclonal antibody obinutuzumab (Gazyva) to standard therapy for lupus nephritis is more efficacious than standard therapy alone, according to a new phase 3, placebo ...

There are few data concerning maintenance therapy for lupus nephritis. 8,11 A suboptimal response to treatment in patients with class III, IV, or V lupus nephritis increases the risk of end-stage ...

DUBLIN, Sept. 20, 2019 /PRNewswire/ -- The 'Lupus Nephritis (LN) - Market Insights, Epidemiology and Market Forecast to 2028' drug pipelines has b ...

The sBLA is supported by data from the randomized, double-blind, placebo-controlled phase 3 REGENCY study (ClinicalTrials.gov Identifier: NCT04221477), which included patients with International ...

If you have lupus nephritis, it’s important to continue to get regular urine tests to monitor how well your kidneys are working — even if you’re being treated for lupus nephritis. According to the ACR ...