This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

Watson and Crick's discovery of DNA structure in 1953 revealed a possible mechanism for DNA replication. ... As the double helix unwinds, it creates a loop known as the replication bubble, ...

The first step in DNA replication requires the assembly of a group of proteins called the Origin Recognition Complex (ORC). Researchers have determined how the ORC assembles during the cell ...

As the replication bubbles progress along the DNA molecule, they eventually fuse, resulting in two complete and identical DNA molecules. The dance of precision: Coordinated replication.

The bubble-like mode of DNA replication can operate in non-dividing cells, which is the state of most of the body's cells, making this kind of replication a potential route for cancer formation. " ...

DNA replication and replication stress. In eukaryotes, DNA replication initiates at many replication origins that are distributed along the length of each chromosome arm. At each origin, two ...

Protein involved in balancing DNA replication and restarting found USP50 protein helps balance nuclease and helicase activity during critical processes ...

Their findings, which were published March 7 in Science, one of world’s leading scientific journals, not only reveal new details about how secondary DNA structures like G4s can impede DNA replication, ...

Cell-like bubbles that can grow and self-replicate like living ... that carry information about themselves and use this for replication, as living cells and their information-carrying DNA do.

DNA replication is required to maintain the integrity of genomic information. This article describes the process of DNA replication, in a step-by-step manner.