Plasmacytoid dendritic cells can be activated with viral and bacterial DNA via TLR9. Activated pDCs promote generation of both Th1/Th17 cells [46,76,87,92] and Tregs [104,105].

Identify the key roles of dendritic cells in cancer immunotherapy, including their use as antigen-loaded vaccines and intratumoral adjuvants. 2. Explain the strategies used to overcome tumor ...

Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus ...

In an innovative new study of glioblastoma, scientists used artificial intelligence (AI) to reprogram cancer cells, converting them into dendritic cells (DCs), which can identify cancer cells and ...

Whereas dendritic cells are critical for kickstarting the cancer immunity cycle in the lymph node, ... support T cell ...

Diakonos Oncology’s dendritic cell immunotherapy previously received Fast Track designation for glioblastoma multiforme. Results from a phase 1 trial (ClinicalTrials.gov Identifier: ...

More information: Ignacio Heras-Murillo et al, Immunotherapy with conventional type-1 dendritic cells induces immune memory and limits tumor relapse, Nature Communications (2025). DOI: 10.1038 ...

Researchers from Instituto de Investigación Sanitaria Hospital Universitario de La Princesa and collaborators have developed nanoparticles loaded with poly(I:C) and used them to prime monocyte-derived ...

This allows stem–like T cells to proliferate and to produce new killer T cells that can now kill tumor cells. Part of the body’s natural defense system against cancer involves dendritic cells taking ...

This article reviews select aspects of plasmacytoid dendritic cell biology -- relevant to the disease pathogenesis and immunotherapy in multiple sclerosis.