The Native Antigen Company has announced the release of a highly purified Bordetella pertussis toxin. The product has been developed in response to the increasing pressure on the IVD industry to ...

This was a clue that pertussislike toxins are widespread among pathogenic E. coli, but it was unknown whether the E. coli pertussislike toxin, or EcPlt, works the same way that pertussis toxin does.

Pertussis toxin is able to modify only one specific amino acid in its human G protein target; if that amino acid changes, the G protein is no longer affected by the pertussis toxin.