Cell sheet preparation for use in tissue engineering and regenerative therapies could be significantly improved with the use ...

With the realization that cells interact extensively with their surrounding microenvironments during growth and development, the challenge for researchers has become designing three-dimensional ...

Many cell-based systems give only the barest nod to the ECM by culturing cells on a thin coating of one or a few constituent proteins, like collagen type I. Extending the house analogy, O’Neill ...

“With conventional cell-culture methods, the cells grow flat across the culture dish. This leads to the formation of an unnaturally planar ECM,” Vogel explains. “And anyway, research up to ...

The study uncovers how ovarian ECM tropism influences endometriotic cell adhesion, paving the way for novel strategies to ...

Amsbio has reported positive feedback from researchers using the Cultrex® range of Basement Membrane Extracellular Matrix (ECM) in 3D culture and a wide range of other applications involving promotion ...

Using the same principles as an inkjet printer, the RASTRUM™ allows researchers to combine “bio-inks” with cultivated cells and customizable mixtures of extracellular matrix (ECM for short, which are ...

Organoids—self-organizing, self-reproducing structures that serve as 3D in vitro models—date back to 2009. Back then, researchers at the Hubrecht Institute led by Hans Clevers, PhD, introduced ...