Substrate-assisted catalysis is relatively rare in modern protein enzymes (reviewed in ref. 37), but may represent an evolutionary intermediate in the development of complex enzymes with ...

When the Caltech researchers tested enzymes sitting in their lab fridge, they found that some enzymes that usually did other jobs could also form carbon-silicon bonds. Those enzymes did “very ...

This equation shows that an enzyme and a substrate bind to form an enzyme-substrate complex (ES). This complex then produces the product. As the enzyme is released at the end and not used up in ...

Chemists have coaxed a common enzyme into catalyzing the formation of an enantioselective carbon-nitrogen bond. The approach can generate the preferred enantiomer of amines and anilines within ...

This illustration depicts the process of enzyme catalysis. The enzyme (blue) binds to its substrate (red) to form an enzyme-substrate complex. The enzyme then catalyzes the conversion of the substrate ...

Novel enzyme catalyzing the formation of glycosidic bonds in complex sugar moieties characterized Researchers from Japan determine the precise mechanism of action of a beta-1,2-glucan-associated ...

Image shows the DNMT3A-DNA complex. A research team led by Jikui Song cracked the crystal structure for DNMT3A-DNA complex. The structure reveals that DNMT3A molecules attack two substrate sites ...

These bonds show up in various biomolecules, so there are many enzymes that can manipulate them. But beyond biology, they also show up in a number of plastic polymers that we use on a large scale ...

More information: Yongxin Li et al, Access to Nitrogen–nitrogen Bond-Containing Heterocycles Through Substrate Promiscuity of Piperazate Synthases, ACS Catalysis (2025). DOI: 10.1021/acscatal ...

Scientists crack structure of enzyme complex linked to cancer. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2018 / 02 / 180207140404.htm ...