Escaping the endosome. Unfortunately, even when LNPs reach their target cells, the nanoparticles are typically captured by endosomes—tiny protective sacs within the cell.

Huntington's disease is caused by CAG trinucleotide expansions in the gene encoding huntingtin. N- terminal fragments of huntingtin with polyglutamine produce aggregates in the endosome-lysosomal ...

Interactions between Bacillus thuringiensis Berliner and its beta-exotoxin, thuringiensin, were evaluated in neonate larvae of Spodoptera frugiperda (J. E. Smith). The median lethal concentration of B ...