News

Trisomy is a genetic condition characterized by the presence of an extra chromosome. This means that the affected person has ...
First laboratory to study the adaptation of cancer cells to extra chromosomes. Storchová emphasises the special nature of their research: "Our study is unique in that we are the first laboratory ...
Scientists in Japan have used gene-editing technology to remove the extra chromosome responsible for Down syndrome, at least ...
The nucleus of every human cell contains chromosomes—23 pairs, to be exact. These carry our genetic material, known as the genome, and are composed of deoxyribonucleic acid (DNA) and proteins.
It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells.
Hoping to recreate this effect, Lawrence and first author Dr. Jun Jiang, along with UMMS colleague Dr. Lisa Hall, devised a way to insert the XIST gene into the extra chromosome 21 of trisomic cells.
For patients suffering from Down syndrome, the source of their condition can be traced back to just one extra chromosome inherited during development – chromosome 21. While it is still ...
“The next step will be to silence an extra chromosome in an animal, as opposed to a dish of cells.” For example, they could try the technique on mice that have been bred with extra copies of ...
A comprehensive genetic analysis has found that one in 500 men have an extra sex chromosome, with most unaware. That’s much higher than previously thought, and it seems to increase their risk of ...
The extra chromosome, also known as trisomy 21, causes cellular overactivity, compromises a range of processes within the body, and can manifest in distinctive physical traits, ...
Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the ...
Using CRISPR gene-editing, the team eliminated extra chromosomes from cancer cells and found that they could no longer grow out of control. Healthy human cells have 23 pairs of chromosomes, ...