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Treatment resistance and relapse in the most common type of lung cancer can be traced to a protein called agrin, according to ...
Tumors are held together by a structure called the extracellular matrix (ECM) that acts like the scaffolding around a ...
Understanding the process of extracellular matrix proteolysis was one of our early goals, and we found that ovarian cancer cells produce potent matrix-degrading proteases. 2 Our studies on aging and ...
the tumor vasculature responds by growing vigorously wherever and whenever it can through a heterogeneous extracellular matrix, a process known as invasion percolation (see figure). Using a ...
A new study has identified the protein ADAMTS5 as playing a crucial role in the spread of ovarian cancer cells, offering a ...
But healthy cells are not the only ones that rely on extracellular vesicles. Cancer cells do, too. Small extracellular vesicles that are shed from tumor cells contribute to how cancer spreads to ...
The following is a summary of "Proteomic profiling and functional analysis of extracellular vesicles from ...
Scientists at CNIC have identified a specialized group of neutrophils in the skin that produce extracellular matrix. This ...
recruit tumor-associated macrophages and endothelial cells, and remodel the extracellular matrix. Tumor cells acquire genetic and epigenetic lesions that promote escape from their tissue of origin.
Additionally, we included structural, and cancer related-markers: proliferation (Ki67), stromal cells (a-SMA, MHC I), epithelial cells (E-cadherin, MHC I), extracellular matrix (Tenascin C ...
Hidalgo explains, "The extracellular matrix is critical ... of the study findings for fibrotic processes and cancer. More information: Matrix-producing neutrophils populate and shield the skin ...