The fibroblasts were directly converted into iPULs (induced pulmonary epithelial-like cells)—functionally akin to native AT2 ...

The four-year-old biotech raised about $75 million in a Series A round that involved nine venture capital firms.

More information: Marta Torregrossa et al, Effects of embryonic origin, tissue cues and pathological signals on fibroblast diversity in humans, Nature Cell Biology (2025). DOI: 10.1038/s41556-025 ...

Fibroblasts are the main connective tissue cells present in the body. As well as being present as fibroblasts, these cells exist in an alternative state, as fibrocytes.

The locations of fibroblasts expressing the Col15a1 and Pi16 clusters suggested that the Col15a1 cells, which reside in the internal region of a tissue, might regulate the extracellular matrix ...

Effects of embryonic origin, tissue cues and pathological signals on fibroblast diversity in humans. Nature Cell Biology , 2025; 27 (5): 720 DOI: 10.1038/s41556-025-01638-5 Cite This Page : ...

Fibroblasts play a central role in maintaining healthy tissue structures, as well as in the development and progression of diseases. For a long time, these specialised connective tissue cells were ...

Fibroblasts reprogrammed into AT2-like lung cells in just 7–10 days, offering a faster, safer alternative to stem cell ...

Researchers discovered how anti-cancer drugs called HDAC inhibitors help treat pancreatic cancer by altering scar tissue (fibroblast) development. The findings suggest HDAC inhibitors could be ...

Scientists have found a novel way that includes a new lab-grown material that could help slow and even reverse some of the ...