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When the insulin nanoparticle enters an acidic environment of the stomach, its layers start to repel each other, resulting in the slow release of insulin from the outermost layer, ...
Up to 3% of people with diabetes have an allergic reaction to insulin. A team at Forschungszentrum Jülich has now studied a method that could be used to deliver the active substance into the body ...
Bae and his colleagues found nanoparticle size matters. They fed rodents oral nanoparticles in two sizes (100 or 250 nm) at doses ranging from 1 to 20 mg/kg. Surprisingly, larger nanoparticles were ...
Long-acting insulin might also be used to provide a slow, steady release of insulin. The use of nanoparticles to deliver drug and gene therapy has had a tremendous impact on how diseases are treated.
NTU Singapore scientists have developed insulin nanoparticles that may become an alternative to insulin injections for diabetics. Delivering insulin orally would be preferable over insulin jabs ...
"In this experiment, we exposed mice to a weak electromagnetic field (1 kHz, 21 mT) for just three minutes each day," said Fussenegger. "This controlled their insulin secretion really well and ...
Nanoparticle-driven spleen remodeling allowed transplanted mouse, rat, ... In macaques, human islet grafts sustained insulin and C-peptide release for at least 28 days.
The targeted insulin delivery to the liver is key to reducing hypoglycemia episodes and mitigating adverse effects like weight gain and insulin resistance, common in non-oral administration methods.
Insulin doses vary, so make sure to talk with your doctor, but we'll show you the standards for how to calculate your daily doses and answer your top questions.
The nanoparticles are composed of multiferric cores (Cobalt ferrite and Bismuth ferrite which responsive to magnetic field) and chitosan outer layers ... like insulin, to life." ...