News

Nature14y
Pleiotropic regulation of macrophage polarization and tumorigenesis by formyl peptide receptor-2 | Oncogene - Nature
Cancer cells recruit monocytes, macrophages and other inflammatory cells by producing abundant chemoattractants and growth factors, such as macrophage colony-stimulating factor (M-CSF/CSF-1) and ...
EurekAlert!2mon
Machine learning approach to investigating macrophage polarization on various titanium surface characteristics | EurekAlert!
The polarization response of macrophages seeded on titanium materials is influenced by multiple factors, and artificial intelligence can assist in extracting the key features of implant materials ...
EurekAlert!5mon
Lrrk2 promotes M1 macrophage polarization via regulating cytokine (IFN-γ) and TLR4 (LPS)-mediated responses | EurekAlert!
This study unveiled the role of Lrrk2 gene in regulating macrophage polarization and immune response. This finding provides significant insights into the role of Lrrk2 in M1 macrophage modulation ...
CU Boulder News & Events4y
Varsha demonstrates macrophage polarization control using hMSC-inspired microgel scaffolds | Anseth Research Group - University of Colorado Boulder
Varsha demonstrates macrophage polarization control using hMSC-inspired microgel scaffolds Published:3/23/2021 3/23/2021 Varsha Rao and recently-graduated Dr. Alex Caldwell published this month in ...
ascopubs.org3y
A phase 1/2 dose escalation/expansion study of OR2805 alone or in combination in subjects with advanced solid tumors. | Journal of Clinical Oncology - ASCO Publications
OR2805 treatment reprograms M2 macrophages to take on an immunostimulatory, M1-like phenotype. In macrophage/T cell coculture assays, OR2805 treatment relieved the suppressive effect of M2c ...