Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

Macrophage activation is dependent on receptors, which in turn respond to a variety of external signals. Most of these are mediated by cytokines and antigens present on microbes. Macrophage ...

A receptor on macrophages dictated their ability to reduce inflammation after liver transplant, offering potential ...

Toll-Like Receptors and Dectin-1, a C-Type Lectin Receptor, Trigger Divergent Functions in CNS Macrophages. Journal of Neuroscience , 2015; 35 (27): 9966 DOI: 10.1523/JNEUROSCI.0337-15.2015 Cite ...

Managed Healthcare Executive gives C-suite executives in health plans and provider organizations news and strategies for ...

These function as "eat me" signals to the macrophages, which detect them via Fc receptors (FcR) embedded in their cell membrane. Fc receptors are mobile, and begin to cluster once activated by IgG.

Macrophages actually have two versions of the Fc receptor: One promotes their appetite while the other inhibits it. And both are triggered by IgG. Macrophages have more of the activating version ...

Macrophages actually have two versions of the Fc receptor: One promotes their appetite while the other inhibits it. And both are triggered by IgG. Macrophages have more of the activating version, so ...

M yeloid cells such as monocytes, macrophages, and neutrophils are critical mediators and regulators of immune responses. 1 Derived from hematopoietic stem cells found in the bone marrow, these cells ...

Macrophages have important roles in the induction and resolution of inflammation, but the intracellular pathways from inflammatory signals to pain response remain unclear. a recent study ...

More information: Prior Fc Receptor activation primes macrophages for increased sensitivity to IgG via long term and short term mechanisms, Developmental Cell (2024). DOI: 10.1016/j.devcel.2024.07 ...

Prior Fc receptor activation primes macrophages for increased sensitivity to IgG via long-term and short-term mechanisms. Developmental Cell, 2024; DOI: 10.1016/j.devcel.2024.07.017; ...