“We go on to show that in vitro, human mast cells secrete IL-17A in response to various stimuli which have been suggested to play a role in RA,” says McInnes. These stimuli included tumor ...

Japan’s pet cancer therapeutics sector surges forward, propelled by evolving diagnostic tools, innovative drug breakthroughs, ...

They tend to be movable and are not painful to the touch (unlike an abscess or mast cell tumor) and the skin over them is ...

mast cells, etc.) as well as adaptive immune cells (T cells and B cells): CAFs stimulate the polarization of innate immune cells towards pro-tumor subtypes through direct contact, paracrine ...

Common types in senior dogs include mast cell tumors, lymphoma, hemangiosarcoma, squamous cell carcinoma, oral melanomas, and ...

In dogs, tigilanol tiglate provides a first-line alternative to surgery in non-metastatic mast-cell tumors, meeting an unmet need in the veterinary market. Its launch as Stelfonta in USA ...

The researchers found that a compound called SYM2081 inhibited inflammation-driving mast cells in mouse models and human skin samples, paving the way for new topical treatments to prevent itching ...