The question perhaps is not when native mass spectrometry can be used; but rather, when can’t it be used? Today, the applications are broad-reaching and diverse. This article shares insights from ...

Pharma set to reap the rewards of advances in native mass spectrometry In bottom-up proteomics , proteins are digested into peptides and typically separated via liquid chromatography before being ...

A technique called native state mass spectrometry could allow scientists to evaluate how potential inhibitors work on antibiotic-resistant bacteria, according to a study presented at the World ...

Using native ambient mass spectrometry (NAMS) imaging, scientists can visualize the spatial distribution of proteins and their complexes in thin tissue sections and gain valuable insights into ...

Acyl carrier protein (ACP) plays a central role in fatty acid biosynthesis, acting as a molecular "shuttle" that carries, protects, and delivers elongating acyl chains to various enzymatic partners.

During clathrin-mediated endocytosis, adaptor proteins bind to the cell membrane and to the protein clathrin, assisting in ...

When scientists analyze proteins with mass spectrometry, they typically denature the biomolecules, causing the proteins’ biologically relevant forms and composition to disappear. In contrast, so ...

Thermo Fisher Scientific explains how high-resolution accurate-mass mass spectrometry (HRAM–MS) can be used to study mAbs and derive insights from complex samples.

For large molecules and complex mixtures, conventional mass spectra can become too complicated to interpret. New technologies including various forms of charge-detection mass spectrometry, mass ...

Native mass spectrometry is affording crucial insights to how potential bacterial protein inhibitors could combat antibiotic resistance. Research presented at the World Microbe Forum (online, 20–24 ...