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NeuM technology revolutionizes neuron labeling for neurodegenerative disease research. Download PDF Copy; Reviewed. National Research Council of Science & Technology Apr 8 2024.
Using the current technology 15, one can, in theory, uniquely label homozygous null mutant cells in the Cre/Lox system by inserting a marker gene after the transcription stop in the 'floxed' allele.
Development of 'NeuM', a neuron labeling technology enabling detailed observation of neuronal structure. Successful monitoring of neuronal changes for up to 72 hours. Peer-Reviewed Publication ...
Called SLICK—for single-neuron labeling with inducible Cre-mediated knockout—the method labels individual neurons and knocks out targeted genes at the same time. The researchers used SLICK to study ...
It relied on a relatively new neuron-labeling technology known as FlashTag (FT). The study shows that instead of always producing more of the same cells, ...
Live-cell dyes are convenient, inexpensive, and rapid neuron culture labeling alternatives. Additionally, automated microscopy and image analysis techniques support researchers performing high-content ...
Armed with these details of steady-state tau levels, Sato and colleagues set out to track tau kinetics using stable isotope labeling kinetics (SILK). The researchers added 13 C-leucine to the neuron ...