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Understanding muscle developmentThe research team found that a specific muscle protein, known as MEF2C, is significantly reduced in muscle cells with CP.
RNA performs a given function itself (non-coding RNA, or ncRNAs). Human genome and transcriptome sequencing show that approximately 76 % of the genome is transcribed, but only 2 % of this codes ...
High expression of the RNA predicted a poor prognosis, the team found. But, Diederichs notes, “we didn’t find a remarkable open reading frame, and we didn’t find any protein expressed from it. We ...
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Key molecule in wound healing identified through mapping of long non-coding RNA moleculesResearchers have now mapped lncRNA (long non-coding RNA molecules) in human skin wounds in tissue samples from Karolinska University Hospital, identifying a key regulator in wound healing.
Generally, those RNA molecules that do not take the form of mRNA are referred to as noncoding, because they do not encode proteins. The involvement of noncoding mRNAs in many regulatory processes ...
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A new tool for plant long non-coding RNA identificationLong non-coding RNAs (lncRNAs ... This study extensively collected high-quality RNA-sequencing data from various plants and utilized these plant-specific data to retrain the models of three ...
See how small bits of non-coding RNA target mRNA for destruction and regulate gene expression. Evidence has also shown that siRNA is involved in antiviral defense in certain plant and animal species.
A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.
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Hannover-based Cardior specialises in the discovery and development of therapeutics targeting non-coding RNA – sequences that don’t code for proteins, but which are thought to be important ...
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