The utility of cancer cell lines is affected by the similarity to endogenous tumour cells. Here we compare genomic data from 65 kidney-derived cell lines from the Cancer Cell Line Encyclopedia and ...

These lines offer ready availability of cells that express normal phenotype and function. The groups’ cells are now widely used in academic and commercial laboratories across the world and provide ...

All three patients have had normal kidney function without any ... and irradiated Epstein–Barr virus–transformed lymphoblastoid cell lines derived from both parents of the ...

In normal renal epithelia, polycystin-1 is confined to lateral cell membranes at sites of cell–cell adhesion (adherens junctions) and cell–matrix contacts (focal adhesions), whereas in cystic ...

Chronic kidney disease (CKD) is typically associated with severe fibrosis, the exact pathogenesis of which remains unclear.

This therapy uses drugs or other substances to find and target cancer cells with less toxicity to normal cells. ... This treatment is not typically a first-line treatment for kidney cancer.

Papillary renal cell carcinoma (PRCC) is a type of cancer that forms inside the lining of the kidney tubules. Learn more about the signs and treatments.

The type of kidney cancer tells your doctor what sort of kidney cell it started in. The grade tells them how much the cancer cells look like normal cells. Knowing about the type and grade of kidney ...

There are several treatments for metastatic renal cell carcinoma (RCC), including surgery, targeted treatment, and chemotherapy. But in some cases, you might stop responding to targeted therapy ...