Nucleophilic substitution reaction: A process in which a nucleophile displaces a leaving group from an organic substrate, often proceeding via a concerted or stepwise mechanism.

In undergraduate organic chemistry courses, nucleophilic substitution reactions are often carried out as an experiment. Reactions that occur at saturated carbons are chiefly categorized as S N 1 or S ...

Using the now-decommissioned Summit supercomputer, researchers at the Department of Energy's Oak Ridge National Laboratory ...

Understanding the delicate balance between nucleophilicity and electrophilicity is fundamental to rationalising reaction mechanisms in organic chemistry. Nucleophilic reactivity describes a ...

At the air-water interface, a negatively charged amino acid carries out a nucleophile attack on a gas molecule to convert it into a product. The ...

An electric field could make an unlikely nucleophilic substitution reaction feasible by fixing the reactants in place and lowering the reaction energy barrier, according to a theoretical study (J ...

Nucleophilic substitution reaction occur with two mechanism that is SN 1 & SN 2. The detail about the reaction mechanism and how the complete reaction takes place, ...