Moreover, PASI 90 and PASI 100 scores were the highest for the head and neck region, indicating the highest response rates, while those for the lower extremities were consistently low at all visits.

Early response rates to these therapies were then examined for stable long-term response, as measured by associations with maintaining complete (PASI 100) or almost complete (PASI 90) skin ...

The five ranked secondary efficacy end points were a PASI 100 response (complete skin clearance) at week 16, a PASI 75 response (≥75% reduction from baseline in the PASI score) at week 4, a PASI ...

Patients in either treatment group who did not have at least a 75% improvement in the PASI score and a score on the PGA of 0 or 1 at week 24 or in whom the response was lost (i.e., had less than a ...

The emergence of new therapeutic classes for psoriasis has brought into focus the need to "set the bar higher" and adopt PASI 90 as the new standard for a good response, Pariser said. Rates of ...

It has recently been claimed that patients who achieve PASI scores less than or equal to 2 within the first 6 months of initiating biologic treatment tend to exhibit more stable psoriasis and a ...

Other secondary endpoints included PASI 100 response and Investigator’s Global Assessment (IGA) scores of 0 and 1. At week 48, a greater proportion of guselkumab-treated patients achieved PASI ...

Of the patients who had a PASI 75 response at week 24, 82% (187/228) had this continued response at week 52. For those who had a PASI 90 response at week 24, 74% (103/140) had this continued ...

The rates of response were 53%, 61%, and 64% for the 20-mg, 30-mg, ... At 4 weeks, PASI scores climbed from baseline by nearly 40% for those on all orismilast doses, ...

PASI 100 rates at the same time points were 27% and 40% among patients switched from placebo to icotrokinra. IGA 0 response rate increased from 1% at 16 weeks to 23% at 24 weeks, and PASI 100 ...

The Can-Fite Phase III study will evaluate the proportion of subjects who achieve a Psoriasis Area and Severity Index (PASI) score response greater than or equal to 75%, PASI 75 at week 16.