Effective therapy of septic shock requires knowledge of its pathogenesis, anticipation and recognition of the clinical picture, the use of available bedside and laboratory technics for assessing ...

Sepsis, or septic shock, is an excessive inflammatory response in answer to a serious infection, most commonly by bacteria, but also fungi, viruses, and parasites.

Septic shock, or sepsis, is a medical condition in which acute inflammation, ... but up to now NO remained a prime suspect for the pathogenesis of the cardiovascular shock.

Improved understanding of the pathogenesis of severe sepsis and septic shock has led to the development of new therapies that place importance on early identification and aggressive management. This ...

In septic shock, the severest stage of sepsis, ... "We exploited the leakiness of the BBB, a hallmark pathophysiology of the systemic inflammatory syndrome, ...

A post hoc analysis involving 348 patients with septic shock (56% of the overall population) had similar results. 20 The second trial 13 was a single-center, randomized, controlled trial that ...