FoundationOne Germline More is an expanded NGS panel analyzing 154 genes, including well-established cancer-related genes and candidate genes with emerging evidence of association with cancer risk.

A new study by researchers at the Hebrew University of Jerusalem (HU) has revealed unexpected and sex-specific effects of germline regulation on longevity.

Below is shown: 1) Cultured muscle stem cells. 2) An image of skeletal muscle in cross-section (laminin is green) 3) Flow cytometry of muscle stem cells from a from a Pax7 CreERT2;LSL tdTomato mouse.

The study revealed unexpected and sex-specific effects of germline regulation on longevity and somatic repair in vertebrates. Contrary to classical evolutionary theories, it turns out that ...

CHICAGO — An online platform may help increase access to and reduce barriers associated with germline testing for individuals with cancer, according to findings presented at ASCO Annual Meeting ...

ASCO endorses the need for patients to make informed decisions prior to proceeding with germline testing. 4,15 Furthermore, somatic testing may uncover potential germline findings, and therefore, ...

Study: Germline-encoded specificities and the predictability of the B cell response.Image Credit: Kateryna Kon/Shutterstock.com Background. Although the evolution of the immunoglobulin genes that ...

Leggat et al. designed a germline-targeting, self-assembling nanoparticle immunogen, eOD-GT8, which presented 60 copies of an engineered HIV envelope protein containing mutations designed to ...

“It’s known that germline structural variation also can contribute to the molecular profile of cancers,” Creighton said. “Here we study the extent of its contribution.” The researchers worked with ...

Undergoing germline testing is of particular importance for patients with prostate cancer, as one expert explained. “Germline testing is that genetic testing of the of the sequence of DNA that you ...

Intellia plays down concerns about accidental germline transmission in CRISPR trial. By Megan Molteni Aug. 21, 2023. Reprints. Adobe.