Bacterial CD-NTases produce a wide range of cyclic oligonucleotides but have not been documented to produce 2′,3′-cGAMP. Here we discovered bacterial CD-NTases that produce 2′,3′-cGAMP to restrict ...

The lytic and lysogenic cycles are the two main phases of a virus’ infective lifecycle and route to replication. The lytic cycle, or virulent infection, involves a virus taking control of a host cell ...

Regulation of phage lambda packaging motor-DNA interactions: Nucleotide independent and dependent gripping and friction. eLife , 2023 DOI: 10.7554/eLife.91647.1 Cite This Page : ...

Their efforts have been focused on 'bacteriophages' - viruses that rely on bacterial hosts for replication. One of the most intensively studied and best characterized of these is the 'lambda phage'.

Viruses depend on host cells for replication, but how does a virus induce its host to transcribe its own genetic information alongside that of the virus, thus producing daughter viruses? For decades, ...

Damaged DNA leads straight to evolution’s landfill because it’s useless for the phage that needs it to reproduce. So lambda turns on its replication genes, makes copies of itself and bursts ...

Viruses depend on host cells for replication, ... One of the most intensively studied and best characterized of these is the 'lambda phage'.