Phosphatidylserine (PtdSer) is a phospholipid that is abundant in eukaryotic plasma membranes. An ATP-dependent enzyme called flippase normally keeps PtdSer inside the cell, but PtdSer is exposed ...

In yeast, polarized localization of Cdc42 is essential for budding and mating, but how polarity is attained has been elusive. Grinstein and colleagues show that phosphatidylserine accumulates in a ...

Health Benefits The vitamins, minerals, and micronutrients in phosphatidylserine provide some important health benefits. Phosphatidylserine is known to act as an antioxidant, helping reduce the ...

The externalization of phosphatidylserine (PS) is arguably the most emblematic eat-me signal that is in turn bound by a large number of serum proteins and opsonins that facilitate efferocytosis.

Viral apoptotic mimicry, defined by the exposure of phosphatidylserine on the pathogen surface, is emerging as a common theme used by enveloped viruses to promote infection. In this Progress ...

Article CAS PubMed PubMed Central Google Scholar Elliott JI, Sardini A, Cooper JC, Alexander DR, Davanture S, Chimini G et al. Phosphatidylserine exposure in B lymphocytes: a role for lipid packing.

The apoptotic event of phosphatidylserine exposure and its recognition by the receptor BAI1 has an unexpected new role as a signal enhancing mouse myoblast fusion, an insight with relevance to ...

Recognition of phosphatidylserine (PtdSer) is essential for engulfment of apoptotic cells by mammalian phagocytes. Engagement of a new phosphatidylserine-specific receptor (PtdSerR) appears to be ...