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In this study, we have demonstrated, using two independent normal podocyte cell lines, a previously unsuspected aspect of human podocyte biology: that differentiated podocytes are insulin ...
From: “MicroRNAs in Podocyte Injury in Diabetic Nephropathy” Ishii et al. 2020 . When the kidneys experience a bacterial or viral attack, podocytes begin retracting their foot projections.
SAN DIEGO, June 11, 2025--Travere Therapeutics today announced that the Company will present three abstracts at the upcoming International Podocyte Conference.
Podocytes are a terminally differentiated cell type located in the glomerulus. Podocyte damage and the subsequent dysregulation of podocyte proteins have been implicated in various kidney disorders.
LONDON, UK I July 09, 2025 I Purespring Therapeutics, a precision nephrology company focused on transforming the treatment of kidney diseases, today announces ...
Podocyte culture: tricks of the trade. To find out more about this Human Podocyte cell line, read Prof. Saleem’s article in Nephrology. Professor Moin Saleem. Dr. Moin Saleem is a Professor at the ...
Primary human cell derived (excluding murine podocyte cell line) Physiologically relevant phenotype analogous to in vivo differentiated renal cells. Homogenous, stable and long-lasting; ...
PEMP analysis confirmed that ELX-02 treatment improved podocyte foot process effacement in all three patients with an average post-treatment increase in FSD of 60% as compared to baseline levels.
A New Era of Podocyte-Targeted Therapy for Proteinuric Kidney Disease Author : Börje Haraldsson , M.D., Ph.D. Author Info & Affiliations Published December 19, 2013 ...
Using 2-DOG uptake assays, we found that two independent podocyte cell lines were each capable of increasing their glucose uptake by 90 and 105%, respectively, after 15 min of stimulation with 220 ...