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To identify the culture conditions supporting podocyte progenitor growth, cryopreserved cells from the primary cultures (P0) were plated on various substrates including plastic, ...
In this study, we have demonstrated, using two independent normal podocyte cell lines, a previously unsuspected aspect of human podocyte biology: that differentiated podocytes are insulin ...
From: “MicroRNAs in Podocyte Injury in Diabetic Nephropathy” Ishii et al. 2020 . When the kidneys experience a bacterial or viral attack, podocytes begin retracting their foot projections.
SAN DIEGO, June 11, 2025--Travere Therapeutics today announced that the Company will present three abstracts at the upcoming International Podocyte Conference.
Podocytes are a terminally differentiated cell type located in the glomerulus. Podocyte damage and the subsequent dysregulation of podocyte proteins have been implicated in various kidney disorders.
Primary human cell derived (excluding murine podocyte cell line) Physiologically relevant phenotype analogous to in vivo differentiated renal cells. Homogenous, stable and long-lasting; ...
Podocyte culture: tricks of the trade. To find out more about this Human Podocyte cell line, read Prof. Saleem’s article in Nephrology. Professor Moin Saleem. Dr. Moin Saleem is a Professor at the ...
PEMP analysis confirmed that ELX-02 treatment improved podocyte foot process effacement in all three patients with an average post-treatment increase in FSD of 60% as compared to baseline levels.
A New Era of Podocyte-Targeted Therapy for Proteinuric Kidney Disease Author : Börje Haraldsson , M.D., Ph.D. Author Info & Affiliations Published December 19, 2013 ...
LONDON, UK I July 09, 2025 I Purespring Therapeutics, a precision nephrology company focused on transforming the treatment of kidney diseases, today announces ...
Using 2-DOG uptake assays, we found that two independent podocyte cell lines were each capable of increasing their glucose uptake by 90 and 105%, respectively, after 15 min of stimulation with 220 ...