Podocytes are specialised cells of the renal corpuscles (glomeruli) that play a crucial role in the filtering function of the kidney. Their size and density are important indicators of the health ...

Podocytes demonstrate a strong reliance on insulin to function properly, according to a study published in Cell Metabolism (2010;12:329-340).

This confirmation of mature podocytes gives kidney researchers across the scientific community a tool for investigating human kidney development, function, and disease; these cells also could ...

Podocytes are the main source of VEGF in the kidney: mice lacking VEGF specifically in podocytes show partial loss of all major cell types in the glomerulus, including podocytes 5, 6.

Protection of podocytes will be of paramount importance in preventing the development and progression of diabetic nephropathy.

A new research paper was published in Aging's Volume 15, Issue 14, entitled, “Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span.” ...

Kidney podocytes, all grown up New protocol produces large numbers of mature human podocytes Date: July 11, 2018 Source: Wyss Institute for Biologically Inspired Engineering at Harvard Summary ...

A new study has illustrated that inhibiting NLRP3 signaling in aging kidney cells reduces inflammation and improves their life- and health-span.

Furthermore, B7-1 immunostaining of podocytes was observed in the allograft specimen from a patient with recurrent FSGS, whereas the allograft specimens from all the other patients were negative.

Our data demonstrate that targeting podocytes to modulate complement activation is an effective therapeutic strategy, and PS-002 paves the way to become the first gene therapy in development for ...

The results show that high blood pressure can lead to abnormalities in the podocytes, specialized cells in the renal filter, even without other pre-existing conditions such as diabetes.

A new research paper titled "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span" has been published in Aging.