Experiments that construct or discover protein point-mutations and investigate their functional consequences represent one of the cornerstones of biomedical investigation. And yet, despite the ...

The discovery may explain why cutting edge CAR T-cell therapy has managed to revolutionized treatment for blood cancer but ...

An international research team led by Justus Liebig University Giessen (JLU) and the Joint FAO/IAEA Center of Nuclear ...

A recent paper by Syed et al. demonstrates that mutations in the Nucleocapsid (N) protein, one of the four structural proteins in SARS-CoV-2 in addition to the Spike protein, plays a critical role ...

Mutations are unique effects that your character can have in Caves of Qud. These mutations can be simple, such as the ...

The prognostic significance of point mutations in patients with myelodysplastic syndromes may be driven by the association of these mutations with risk factors, including karyotype, blast ...

Comprehensive biomarker testing can identify EGFR or other mutations in your lung cancer. Learn the benefits of testing and how it can help shape treatment.

Some people can feel well-rested and show no negative effects of sleep deprivation, even after just 4 hours of sleep, which is likely the result of a genetic mutation. A recent study ...

The team went on to show that the V617F mutation produced a constitutive JAK2 activation in erythroid progenitor cells, causing spontaneous STAT-mediated transcription even in the absence of ...

In this paper, we report a mutation in XNP, segregating in a family presenting an ‘ATR-X’ phenotype without α-thalassemia, that causes a proline to serine transition in the helicase II domain.

Mutation induction, together with mutation detection a key element of mutation breeding, has been an important tool for plant breeders for more than 70 years to increase the genetic diversity of ...