Mutations generally fall into two types: point mutations and chromosomal aberrations. In point mutations, one base pair is changed. The human genome, for example, ...

Point mutations are where one nucleotide in a genomic sequence is replaced or substituted with another. 6 Chromosomes can fuse, ... This type of mutation is also known as an inherited mutation.

A study published in Cell Stem Cell reveals that some mutations in blood stem cells might help protect against late-onset ...

Classical EGFR mutations such as EGFR 19 deletions and EGFR L858R point mutations tend to respond best to TKIs. Rarer types of mutations, such as the EGFR exon 20 insertions, don't respond as well ...

Scientists have made a rare discovery that allows them to attribute two types of tumour almost entirely to specific mutations that lie in two related genes. Chondroblastoma and giant cell tumour ...

Drug addiction mutations lead to some of the cancer cells using the drug to help them grow, instead of destroying them. For these types of mutations the study results support the use of “drug ...

Studying the function, rate, type and distribution of point mutations can therefore give us insights into the evolutionary pressures on bacterial pathogens. Function.

"By gaining the mutations, both cell states can give rise to leukemia, but with distinct biological properties that respond ...

EGFR-positive lung cancer is a type of non-small cell lung cancer (NSCLC). It can cause symptoms such as breathing problems and hoarseness. Therapy that targets the mutation, such as EGFR ...

During the past two decades, ion beam radiation has emerged as an effective and unique mutagen. Other types of mutagenic radiation, such as X-rays, α- and β-particles, fast neutrons or UV light have ...