They validated the archetypes using previously published RNA sequencing data of 158 bone metastases across 10 cancer types. The team found that archetype does not always coincide with tumor origin.

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The Revelo RNA-Seq kit was developed in response to an urgent need for faster, easier pathogen library preparation from low copy number or degraded sample types, such as nasal swabs.

Citation: Single-cell RNA sequencing of bone metastases from multiple cancer types reveals three distinct immune archetypes (2025, May 23) retrieved 27 June 2025 from https://medicalxpress.com ...