SETD2, known for its involvement on gene expression, also can affect functions controlled by the cytoskeleton, such as movement, metastasis and migration, which are very important for cancer cells.

The actin cytoskeleton is a dynamic network made up of actin polymers and associated actin binding proteins. The actin cytoskeleton was originally isolated as a component of the actomyosin complex ...

Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity. Cancer Research , 2018; 78 (19): 5631 DOI: 10.1158/0008-5472.CAN-18-0441 Cite This Page : ...

The cytoskeleton provides most cells with their shape, structure, and internal organization. In turn, the cytoskeleton relies on a type of actin protein, called filamentous or F-actin.

Manipulation of the host cell actin cytoskeleton is a common feature for many viruses. In this Review, Taylor, Koyuncu and Enquist describe how the interaction of viral proteins with the actin ...

The cytoskeleton of a cell is made up of microtubules, actin filaments, and intermediate filaments. These structures give the cell its shape and help organize the cell's parts.

Imaging the actin cytoskeleton in presynapses is not easy as the abundance of the protein in the postsynaptic terminal often obscures its presence in the presynaptic one, Leterrier explained. Genome ...

Study identifies key protein that helps regulate the actin cytoskeleton. A recent study led by Assistant Professor of Gerontology Ryo Sanabria has identified a key protein that helps regulate the ...

An interdisciplinary team lead by Peter Bieling and Stefan Raunser from the Max Planck Institute of Molecular Physiology in Dortmund has now revealed a previously unknown mechanism, explaining how ...

The actin cytoskeleton is essential for maintaining the shape of cells and enabling motility, and plays critical roles in tumor cell invasion and metastasis.

The actin cytoskeleton provides force for dynamic cellular processes, such as motility, morphogenesis, cell division, endocytosis, and phagocytosis. The organization and dynamics of actin filaments ...

More information: Antoun Al Absi et al, Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer–Mediated Cytotoxicity, Cancer Research (2018). DOI: 10.1158/0008-5472 ...