In severe cases of tissue death, there’s a possibility of amputation. This is commonly performed on arms, legs, fingers, or toes . Calciphylaxis isn’t curable, but remission is possible.

This month, the Food and Drug Administration approved the first therapy for treatment of severe frostbite in the country. This month, ...

The FDA on Wednesday approved the first medication injection to treat severe frostbite. Aurlumyn, which has the active ingredient iloprost, reduces the risk of finger or toe amputation, the FDA said.

Sixteen consecutive below-knee amputations were carried out in 15 patients because of actual or impending gangrene of the foot. The gangrenous areas extended to the heel in 5 limbs, but in no ...

One of them, calciphylaxis, typically affects patients with end-stage, advanced kidney disease. It is a condition characterized by severe, painful and non-healing skin ulcers with no known cure.

Severe Frostbite Gets a Treatment That May Prevent Amputation The F.D.A. recently approved the first therapy for patients in danger of losing their toes, fingers and other exposed parts of the ...

Activation and targetability of TYMP–IL-6–TF signaling in the skin microenvironment in uremic calciphylaxis. Science Translational Medicine , 2025; 17 (795) DOI: 10.1126/scitranslmed.adn5772 ...

The first time Dr. Peter Hackett saw a patient with frostbite, the man died from his wounds. It was in Chicago in 1971, and the man had gotten drunk and passed out in the snow, his fingers so froze… ...

News; Nation/World; Severe frostbite gets treatment that may prevent amputation Feb. 24, 2024 Updated Sat., Feb. 24, 2024 at 6:41 p.m. New Zealand climber Mark Inglis, a double-amputee, shows the ...