Individuals with sickle cell disease – a chronic illness where misshapen, sticky blood cells clump together, reducing oxygen delivery to organs – are at a higher risk for stroke and resulting ...

The sickled cells can clump and block blood flow. ... Children with sickle cell disease should take penicillin from ages 2 months to 5 years. Some adults will also need to take antibiotics, ...

The first healthy volunteer has been dosed in a Phase 1 study of Cellarity's novel globin-switching therapy CLY-124 for ...

For people with SCD, hemoglobin S (a mutated protein that transports oxygen) causes red blood cells to become curved (sickle-shaped) and stiff. This disrupts how easily red blood cells and the oxygen ...

Sickle cell disease fundamentally changes how red blood cells function in the body. ... making it thicker and more likely for sickled cells to clump together and block blood vessels.

In patients with sickle cell, the namesake cells form when mutant hemoglobin proteins clump together into fibers, deforming red blood cells’ usual saucer shape into a curved sickle, which ...

Individuals with sickle cell disease -- a chronic illness where misshapen, sticky blood cells clump together, reducing oxygen delivery to organs -- are at a higher risk for stroke and resulting ...

The chronic illness causes misshapen, sticky blood cells that clump together. This reduces oxygen delivery to organs – are at a higher risk for stroke and resulting cognitive disability.

Extreme pain, known as a pain crisis, is one of the hallmark symptoms of SCD. With frequent hospitalizations, chronic pain ...

Families of those who have sickle cell disease in the Philadelphia area are pushing for more research and a cure.