“Sickle cell disease is a rare, debilitating and life-threatening blood disorder with significant unmet need," the FDA's Dr. Nicole Verdun said in a statement announcing the approvals.

Sickle cell disease is a group of inherited disorders in which red blood cells — normally round — become hard, sticky and crescent shaped. The misshapen cells clog the flow of blood, ...

But the reality of what that meant hit home in 2017 when one of their twins, Nazaneen, was diagnosed with sickle cell disease (SCD) when she was just an infant. Nazaneen, who is now 5, ...

CNN staffer Sharon Browne-Peter was diagnosed with sickle cell disease before she was born and needs regular blood transfusions to stay healthy. Ethnically-matched blood offers the best treatment ...

Sickle cell affects millions of people around the world, including about 100,000 in the U.S. A genetic defect causes bone marrow to produce a defective version of the protein called hemoglobin.

A panel of experts said on Tuesday that a groundbreaking treatment for sickle cell disease was safe enough for clinical use, setting the stage for likely federal approval by Dec. 8 of a powerful ...