However, Koh's newly synthesized substrate retains a short hemicellulose tail attached to the reaction site, and it turned out that it is this tail that the enzyme binds to when performing its role.

The serine proteinase plasmin is the key fibrinolytic enzyme that dissolves blood clots and also promotes cell migration and tissue remodeling. Here, we report the 2.65 Å crystal structure of a ...

A novel mechanism of DNA endonucleolytic cleavage has been visualized for the homing endonuclease I-PpoI by trapping the uncleaved enzyme–substrate complex and comparing it to the previously ...