Tight junctions are intercellular adhesion complexes in epithelia and endothelia that control paracellular permeability. This paracellular diffusion barrier is semipermeable: it is size- and ...

This sealing is achieved through structures called tight junctions. However, how these tight junctions form has long been a ...

Tight junctions are one mode of cell–cell adhesion in epithelial and endothelial cellular sheets. They act as a primary barrier to the diffusion of solutes through the intercellular space ...

Progressive Proximal-to-Distal Reduction in Expression of the Tight Junction Complex in Colonic Epithelium of Virally-Suppressed HIV Individuals. PLoS Pathogens , 2014; 10 (6): e1004198 DOI: 10. ...

The tight junction complex forms tiny strands to seal that intercellular space. Levine and colleagues demonstrated in their investigation that patients whose HIV was well controlled with ...

Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, ...

Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, claudin 18 ...

A team led by researchers at St. Jude Children's Research Hospital report that mice lacking the protein Alix develop hydrocephalus or "water on the brain." Alix ensures that epithelial cells of ...

Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, claudin 18 ...

Tight junctions must be able to adapt to cell shape change and still be able to seal the gaps," explains Prof. Honigmann, chair of Biophysics and research group leader at the BIOTEC.

By interacting with the actin cytoskeleton, underneath the cell outer membrane, and other structural proteins of the tight junctions, Alix ensures the formation of the actomyosin-tight junction ...