Protein toxicity: The overexpression of transmembrane proteins, ... Elofsson A. A study of the membrane-water interface region of membrane proteins. Journal of Molecular Biology, 367(1), 1071-1082.

Before this study, little was known about the structures of transmembrane proteins or how the interiors of the three classes were related. The study was published in the journal Proteins on Feb. 10.

Improved technology for reconstructing cryo-electron microscopy (cryo-EM) images has now made it possible to determine secondary structural features of membrane proteins in enveloped viruses. The ...

This is especially the case for the generation of therapeutic antibodies directed at complex, multiple transmembrane targets including G protein–coupled receptors (GPCRs), ion channels, and ...

New research combines two powerful imaging techniques to study the complete structure of a common aGPCR, including how its long and complex extracellular region interacts with the transmembrane ...

TMEM158 ( Transmembrane Protein 158) : Redefining Ovarian Cancer Care Written by Dr. Bhavani Gunasekaran , Dr. Navapriya S Medically Reviewed by Dr. Avinash Ramani M.Sc, Ph.D ( Bioinformatics) on ...

Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors ... it can move and interact with the transmembrane region to initiate signaling, ...

Through HT-SPR, faster, more streamlined workflows used to discover therapies targeting transmembrane proteins can be developed. This provides the same amount of information in a fraction of the time ...

Investigation of transmembrane protein fused in lipid bilayer membranes supported on porous silicon. Journal of Medical Engineering & Technology , 2013; 37 (1): 28 DOI: 10.3109/03091902.2012. ...

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