The virus remains dormant until host conditions change, which can result in a switch to the lytic pathway. The decision of the genetic circuit that controls whether a virus initially chooses lysis ...

For this study, the researchers analyzed the decision circuit that determines whether a virus initially chooses the pathway that kills the host cell – called the lytic pathway – or the pathway ...

The virus remains dormant until host conditions change, which can result in a switch to the lytic pathway. The decision of the genetic circuit that controls whether a virus initially chooses lysis ...

In the lytic pathway, viral DNA quickly commandeers the host cell's own resources to make hundreds of copies of itself. The new viruses then kill the cell and go on to repeat the cycle in other cells.

The discovery, reported in the journal eLife, also may apply to viruses that infect humans and other animals, the researcher said. Skip to content. Menu. Medical Home Life Sciences Home.

Additionally, phosphomimetic mutation at tyrosine in HSV-2 UL13 downregulated viral replication and pathogenicity in the brain of mice injected with HSV-2, during the active lytic phase (when new ...

Knipe and Cliffe review the mechanisms that underlie the switch from a lytic to a latent infection in the widespread pathogen herpes simplex virus (HSV). They propose a new model in which an ...

Future Microbiol. 2012;7(10):1191-1205. Another viral lytic gene product, vIRF4, was recently identified to be a novel interaction partner of RBP-Jκ. vIRF4 binds the hydrophobic pocket of RBP-Jκ ...

A CORONAVIRUS breakthrough has been made as a new wonderdrug identified by scientists could offer 'hope' for preventing the virus from reproducing.

When the cell divides, the viral DNA also gets duplicated. As long as the infection remains latent, there is little evidence of it in the host. Latent viral infections follow a different course, ...

KS can be classified into four different types [134]. Classic KS is usually an indolent skin disorder primarily affecting Mediterranean elderly men, without relation to HIV infection. Endemic KS ...