Researchers have developed a genetic tool in mice to speed the discovery of novel genes involved in cancer. The system – called PiggyBac – has already been used by the team to identify novel ...

PiggyBac has many advantages over Sleeping Beauty and significantly extends the toolkit available to researchers. But the two systems can also complement one another.

PiggyBac (PB) is known as a highly efficient DNA transposon originally isolated from Trichoplusia ni, and as a promising alternative to Sleeping Beauty (SB). 5 PB can be functional in various ...

Recently, researchers from the United States and China found that a transposon dubbed piggyBac, derived from the cabbage looper moth, can be used to rapidly knock out and insert genes in mice. 1 The ...

Notably, piggyBac transposons can be entirely removed when re-exposed to transposase. Both integration and excision are catalyzed by the piggyBac transposase, ...

This work is published in Nature Communications in the paper, “Non-viral generation of transgenic non-human primates via the piggyBac transposon system.. Although non-human primates are an ...

They're calling it PiggyBac, and it provides biological validation to human mutations. Researchers have developed a new genetic tool in mice to speed the discovery of novel genes involved in cancer.

We have developed novel piggyBac transposon (PB) -based CAR-T cells with favorable characteristics and durable antitumor efficacy against solid malignancies. A GMP-compliant manufacturing process ...

Poseida is a clinical-stage biopharmaceutical company focused on developing cell and gene therapies based on its proprietary platforms, including piggyBac, Cas-CLOVER, and nanoparticle technologies.

Cytomed Therapeutics Ltd. has signed a memorandum of understanding (MOU) with Hangzhou CNK Therapeutics Co. Ltd. allowing Cytomed to utilize CNK's Piggybac technology to permanently graft the chimeric ...

Dr. Molly Duman Scheel, from the Indiana University School of Medicine – South Bend, and Dr. Corey Brizzee, from Demeetra discuss advanced gene editing technologies to create scalable and eco ...

Researchers have developed a genetic tool in mice to speed the discovery of novel genes involved in cancer. The system – called PiggyBac – has already been used by the team to identify novel ...